Science Slots
For convenience, science slots are divided into several categories. The best slots of 2026, new games, slots with high and low volatility, with megaways mechanics, with progressive jackpots and science themed slots with the highest RTP.
Best Science Slots 2026
List of the best science slots at online casinos in 2026. Games are sorted by SlotRank.
Release Date:
2011-11-15
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.6
Max bet $, €, £:
24
RTP:
95.5%
Variance:
MED
Betways:
12
Game Size:
N/A MB
Game Review
Release Date:
2013-05-26
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.5
Max bet $, €, £:
1875
RTP:
93.97%
Variance:
N/A
Betways:
40
Game Size:
N/A MB
Game Review
Release Date:
2015-01-06
Type:
Video Slots
Max Win:
x3076
Min bet $, €, £:
0.15
Max bet $, €, £:
90
RTP:
96.3%
Variance:
MED-HIGH
Betways:
15
Game Size:
N/A MB
Game Review
Release Date:
2016-08-12
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
96.09%
Variance:
MED
Betways:
25
Game Size:
1000 MB
Game Review
Release Date:
2015-04-02
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.4
Max bet $, €, £:
1000
RTP:
95%
Variance:
MED
Betways:
25
Game Size:
1000 MB
Game Review
Release Date:
2013-12-05
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.01
Max bet $, €, £:
500
RTP:
95%
Variance:
N/A
Betways:
20
Game Size:
N/A MB
Game Review
Release Date:
2015-08-12
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.25
Max bet $, €, £:
100
RTP:
0%
Variance:
N/A
Betways:
25
Game Size:
N/A MB
Game Review
Release Date:
2016-03-02
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.5
Max bet $, €, £:
50
RTP:
95%
Variance:
HIGH
Betways:
25
Game Size:
N/A MB
Game Review
New Science Slots
New science casino games released in the last 12 months. Sorted by release date.
MONSTER LAB (Mask On Gaming)
Release Date:
2026-09-17
Type:
Video Slots
Max Win:
x25000
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
96.11%
Variance:
ADJUSTED
Betways:
N/A
Game Size:
N/A MB
Game Review
Release Date:
2026-09-07
Type:
Video Slots
Max Win:
x10000
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
96.31%
Variance:
MED
Betways:
14
Game Size:
29 MB
Game Review
Release Date:
2026-09-07
Type:
Video Slots
Max Win:
x10000
Min bet $, €, £:
0.1
Max bet $, €, £:
10
RTP:
96.31%
Variance:
MED
Betways:
N/A
Game Size:
24 MB
Game Review
Release Date:
2026-09-07
Type:
Video Slots
Max Win:
x25000
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
96%
Variance:
ADJUSTED
Betways:
14
Game Size:
N/A MB
Game Review
Science Casino Slots With The Best RTP
Online science slots with the highest RTP. Please note that for some games, RTP values may vary between casinos.
Release Date:
2013-02-11
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.02
Max bet $, €, £:
100
RTP:
98.09%
Variance:
N/A
Betways:
N/A
Game Size:
N/A MB
Game Review
Release Date:
2022-11-15
Type:
Video Slots
Max Win:
x10200
Min bet $, €, £:
0.2
Max bet $, €, £:
25
RTP:
98.08%
Variance:
HIGH
Betways:
N/A
Game Size:
9.8 MB
Game Review
Release Date:
2016-11-16
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.2
Max bet $, €, £:
120
RTP:
97.7%
Variance:
N/A
Betways:
20
Game Size:
N/A MB
Game Review
Release Date:
2026-05-06
Type:
Video Slots
Max Win:
x10000
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
97.7%
Variance:
N/A
Betways:
14
Game Size:
N/A MB
Game Review
High Volatility Science Slot Machines
Most popular science slot machines with high volatility at online casinos in 2026.
Release Date:
2016-03-02
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.5
Max bet $, €, £:
50
RTP:
95%
Variance:
HIGH
Betways:
25
Game Size:
N/A MB
Game Review
Release Date:
2017-05-05
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.5
Max bet $, €, £:
100
RTP:
95%
Variance:
HIGH
Betways:
25
Game Size:
N/A MB
Game Review
Release Date:
2017-08-01
Type:
Video Slots
Max Win:
x5000
Min bet $, €, £:
0.25
Max bet $, €, £:
12.5
RTP:
94%
Variance:
HIGH
Betways:
25
Game Size:
1000 MB
Game Review
Release Date:
2017-01-25
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.02
Max bet $, €, £:
50
RTP:
96.02%
Variance:
HIGH
Betways:
10
Game Size:
N/A MB
Game Review
Low Volatility Science Online Slots
Science online slots with low volatility, which are the most played recently.
Release Date:
2017-03-03
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.8
Max bet $, €, £:
160
RTP:
96.37%
Betways:
8
(Bothway)
Game Size:
N/A MB
Game Review
Release Date:
2017-04-18
Type:
Video Slots
Max Win:
x550
Min bet $, €, £:
0.2
Max bet $, €, £:
250
RTP:
96%
Betways:
82
Game Size:
1000 MB
Game Review
Release Date:
N/A
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.2
Max bet $, €, £:
200
RTP:
95.72%
Betways:
20
Game Size:
N/A MB
Game Review
Release Date:
2018-03-29
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.2
Max bet $, €, £:
100
RTP:
96.66%
Betways:
20
Game Size:
N/A MB
Game Review
Science Slots With Megaways Mechanics
Top science slots for real money with megaways mechanics.
Release Date:
2020-02-27
Type:
Video Slots
Max Win:
x50000
Min bet $, €, £:
0.1
Max bet $, €, £:
10
RTP:
96.55%
Variance:
HIGH
Betways:
117649
Game Size:
17 MB
Game Review
Release Date:
2023-06-21
Type:
Video Slots
Max Win:
x20000
Min bet $, €, £:
0.2
Max bet $, €, £:
20
RTP:
96.47%
Variance:
HIGH
Betways:
200704
Game Size:
23.3 MB
Game Review
Online Science Slot Games With Progressive Jackpots
Most favorite science slots with with progressive jackpots.
Release Date:
2011-11-15
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.6
Max bet $, €, £:
24
RTP:
95.5%
Variance:
MED
Betways:
12
Game Size:
N/A MB
Game Review
Release Date:
2016-08-12
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.1
Max bet $, €, £:
100
RTP:
96.09%
Variance:
MED
Betways:
25
Game Size:
1000 MB
Game Review
Release Date:
2013-07-29
Type:
Video Slots
Max Win:
N/A
Min bet $, €, £:
0.25
Max bet $, €, £:
125
RTP:
94%
Variance:
N/A
Betways:
243
Game Size:
120 MB
Game Review
Release Date:
2016-12-20
Type:
Video Slots
Max Win:
x1000
Min bet $, €, £:
0.01
Max bet $, €, £:
1000
RTP:
96.1%
Variance:
LOW-MED
Betways:
25
Game Size:
N/A MB
Game Review
N/A 
